Filvordi Dlya Pechati A4

5.0 Fioridella was recommended to us by our wedding coordinator, AMK Events, and they did not steer is wrong!! Teremar at Fioridella is truly gifted and was so nice to work with. They were very reasonably priced for what we wanted and the deocr ended up looking expensive, very bohemian chic and sophisticated. They were able to handle all our flower and decoration needs, including the bouquets, decorating the ceremony space on the beach, the cocktail lounge area, and the dancing/reception space. They gave us solid recommendations for upgrades where needed (made a huge difference) and also saved us money in other areas.

We could not be more satisfied with their work. Highly recommend them!!!

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Fioridella FAQ • What is the average price for a bridal bouquet? $ 150.00 • What is the average price for a bridesmaid bouquet? $ 50.00 • What is the average price for a boutonniere? $ 10.00 • What is the average price for a low table arrangement (per arrangement)? $ 75.00 • What is the average price for an elevated table arrangement (per arrangement)?

$ 150.00 • Typically, what can a customer expect to pay for your wedding floral services? $ 50.00 • Which of the following are included in the cost of your floral services? Consultations, Event Design, Samples, Set Up, Venue Visit • How would you describe your floral designs?

Classic, Modern, Romantic, Rustic, Tropical, Vintage • Which of the following services do you provide? Consultations, Delivery, Event Design, Samples, Set Up, Venue Visit • What types of arrangements do you provide? Aisle Decor, Altar Decor, Bouquets, Boutonnieres, Centerpieces, Chuppah Decor, Corsages, Flower Baskets, Flower Crowns, Flower Petals, Non-Floral, Single Flowers.

This randomized phase II trial studies how well modified irinotecan hydrochloride, leucovorin calcium, fluorouracil (FOLFIRI) and veliparib as a second line of therapy work compared to FOLFIRI in treating patients with pancreatic cancer that has come back after a period of improvement (metastatic). Drugs used in chemotherapy, such as irinotecan hydrochloride, leucovorin calcium, and fluorouracil, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Veliparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It is not yet known whether modified FOLFIRI and veliparib as second line therapy is more effective than FOLFIRI alone in treating metastatic pancreatic cancer. Condition or disease Intervention/treatment Phase Metastatic Pancreatic Adenocarcinoma Recurrent Pancreatic Carcinoma Stage IV Pancreatic Cancer AJCC v6 and v7 Drug: Fluorouracil Drug: Irinotecan Hydrochloride Other: Laboratory Biomarker Analysis Drug: Leucovorin Calcium Drug: Veliparib Phase 2. PRIMARY OBJECTIVES: I. To evaluate the overall survival (OS) of metastatic pancreatic cancer patients treated with fluorouracil, irinotecan (irinotecan hydrochloride), leucovorin (leucovorin calcium), (modified FOLFIRI) and ABT-888 (veliparib) compared to a control arm of fluorouracil, irinotecan, and leucovorin (FOLFIRI).

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SECONDARY OBJECTIVES: I. To evaluate the frequency and severity of toxicity associated with each of the treatment arms in this patient population. To evaluate the progression-free survival (PFS) in each of the treatment arms in this patient population. To evaluate the overall response rate (confirmed and unconfirmed; complete response + partial response), disease control rate (confirmed and unconfirmed; complete response + partial response + stable disease), and duration of response in each of the treatment arms in this patient population.

TERTIARY OBJECTIVES: I. To evaluate if breast cancer, early onset (BRCA)1 and BRCA2 mutations (somatic or germline) are associated with improved clinical outcomes (overall survival [OS], progression-free survival [PFS] and overall response rates [ORR]) in each treatment arm. To evaluate the impact of homologous recombination deficiency (HRD) score on clinical outcomes in each treatment arm.

To evaluate the impact of genomic alterations identified by the BROCA-homologous recombinant (HR) assay, other than BRCA1/2, on clinical outcomes in each treatment arm. To bank tissue for future translational medicine studies. OUTLINE: Patients are randomized to 1 of 2 treatment arms. ARM I: Patients receive veliparib orally (PO) twice daily (BID) every 12 hours on days 1-7, irinotecan hydrochloride intravenously (IV) over 90-120 minutes on day 3, leucovorin calcium IV over 90-120 minutes on day 3, and fluorouracil IV over 46 hours on days 3-5.